AGTRAP antibody

Catalog No. ABIN7111573

This Rabbit Polyclonal antibody specifically detects AGTRAP in ELISA and IHC. It exhibits reactivity toward Human, Rat and Mouse.

Quick Overview for AGTRAP antibody (ABIN7111573)

Target: AGTRAP (Angiotensin II Receptor-Associated Protein (AGTRAP))

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This AGTRAP antibody is un-conjugated

Application: ELISA, Immunohistochemistry (IHC)

Product Details anti-AGTRAP Antibody

Purpose: AGTRAP antibody

Purification: Immunogen affinity purified

Purity: ≥95 % as determined by SDS-PAGE

Immunogen: angiotensin II receptor-associated protein

Isotype: IgG

Application Details

Application Notes: IF: 1:20-1:200, IHC: 1:10-1:100

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze / thaw cycles.

Storage: -20 °C

Storage Comment: -20°C for 12 months

Expiry Date: 12 months

Target Details for AGTRAP

Target: AGTRAP (Angiotensin II Receptor-Associated Protein (AGTRAP))

Alternative Name: AGTRAP

Background:

Synonyms: Type-1 angiotensin II receptor-associated protein|AT1 receptor-associated protein|AGTRAP|ATRAP

Background: Appears to be a negative regulator of type-1 angiotensin II receptor-mediated signaling by regulating receptor internalisation as well as mechanism of receptor desensitization such as phosphorylation. Induces also a decrease in cell proliferation and angiotensin II-stimulated transcriptional activity.

Molecular Weight: 18 kDa

Gene ID: 57085

UniProt: Q6RW13